In my research, I develop computational and statistical methods for population genomics analysis to investigate the forces underlying evolution and genetic variation in populations. Specifically, some things we work on are inferring demographic histories, and studying adaptation using ancient DNA or time series genetic data.
Technical University Berlin
Berlin
PhD - Mathematics
2009Bielefeld University
Bielefeld
Diplom - Computer Science
2006Population Genomic Scans for Natural Selection and Demography.
Population Genomic Scans for Natural Selection and Demography. Annu Rev Genet. 2024 Nov; 58(1):319-339.
PMID: 39227130Inference of population history using coalescent HMMs: review and outlook.
Inference of population history using coalescent HMMs: review and outlook. Curr Opin Genet Dev. 2018 12; 53:70-76.
PMID: 30056275Model-based detection and analysis of introgressed Neanderthal ancestry in modern humans.
Model-based detection and analysis of introgressed Neanderthal ancestry in modern humans. Mol Ecol. 2018 10; 27(19):3873-3888.
PMID: 29603507Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans.
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans. Nature. 2018 01 11; 553(7687):203-207.
PMID: 29323294Computing the joint distribution of the total tree length across loci in populations with variable size.
Computing the joint distribution of the total tree length across loci in populations with variable size. Theor Popul Biol. 2017 12; 118:1-19.
PMID: 28943126The Effects of Population Size Histories on Estimates of Selection Coefficients from Time-Series Genetic Data.
The Effects of Population Size Histories on Estimates of Selection Coefficients from Time-Series Genetic Data. Mol Biol Evol. 2016 11; 33(11):3002-3027.
PMID: 27550904SpectralTDF: transition densities of diffusion processes with time-varying selection parameters, mutation rates and effective population sizes.
SpectralTDF: transition densities of diffusion processes with time-varying selection parameters, mutation rates and effective population sizes. Bioinformatics. 2016 03 01; 32(5):795-7.
PMID: 26556388POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans.
POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans. Science. 2015 Aug 21; 349(6250):aab3884.
PMID: 26198033Transition Densities and Sample Frequency Spectra of Diffusion Processes with Selection and Variable Population Size.
Transition Densities and Sample Frequency Spectra of Diffusion Processes with Selection and Variable Population Size. Genetics. 2015 Jun; 200(2):601-17.
PMID: 25873633A NOVEL SPECTRAL METHOD FOR INFERRING GENERAL DIPLOID SELECTION FROM TIME SERIES GENETIC DATA.
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A NOVEL SPECTRAL METHOD FOR INFERRING GENERAL DIPLOID SELECTION FROM TIME SERIES GENETIC DATA. Ann Appl Stat. 2014 Dec; 8(4):2203-2222.
PMID: 25598858Postdoctoral Research Fellowship
German Research Foundation (DFG)
2011 - 2013Ph.D. Fellowship, International Research Training Group
TU Berlin
2006 - 2009